Correction: Effect of APOE and CD33 on Cognitive Decline
نویسندگان
چکیده
There is an error in the second sentence of the Description of Variables subsection of the Methods section. In Fig 2, the table includes incorrect values. Please see the correct Fig 2 here. Copyright: © 2015 Hayden et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
منابع مشابه
Effect of APOE and CD33 on Cognitive Decline
OBJECTIVE An Alzheimer's disease (AD) diagnosis is preceded by a long period of cognitive decline. We previously demonstrated increased risk of decline among individuals possessing one or more APOE ε4 alleles together with a family history of AD. The objective of this study is to investigate the possibility that such an increased risk might be due to AD risk genes with small effects in combinat...
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Age and APOE are the most robust risk factors for dementia and cognitive decline, but the underlying neurobiology remains unclear. We examined the extent to which the hallmark pathologies of Alzheimer's disease, Lewy body disease, and cerebrovascular diseases account for the association of age and APOE with decline in episodic memory versus nonepisodic cognitive abilities. Up to 20 waves of lon...
متن کاملEffects of the APOE ε2 allele on mortality and cognitive function in the oldest old.
Some studies indicate that the APOE ε2 allele may have a protective effect on mortality and mental health among the elderly adults. We investigated the effect of the APOE ε2 allele on cognitive function and mortality in 1651 members of the virtually extinct Danish 1905 birth cohort. We found no protective effect of the APOE ε2 allele on mortality compared with the APOE ε3 allele. The point esti...
متن کاملStroke and apolipoprotein E epsilon4 are independent risk factors for cognitive decline: A population-based study.
BACKGROUND AND PURPOSE Stroke and apolipoprotein E epsilon4 (ApoE epsilon4) are individually important risk factors for cognitive decline, including Alzheimer disease. It has been suggested that ApoE epsilon4 multiplies the risk for cognitive decline following stroke. In a population-based sample, using well-defined sensitive cognitive measures, this study investigates whether cognitive decline...
متن کاملPii: S0197-4580(01)00223-8
Transgenic mice expressing human APOE-«4 develop an age-dependent decline in memory without pathological features of Alzheimer’s disease (AD). This implicates APOE in the maintenance of memory during normal senescence, but parallel human studies are limited because longitudinal investigations of memory usually do not exclude patients with AD or “questionable” AD (QD). The current study examined...
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